Alexander M, et al. - In this investigation, researchers assessed over 18 million adult healthcare records to estimate the risk of acquiring advanced diagnoses of liver disease in non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH) patients vs individually matched controls. Out of 18,782,281 adults, a total of 136,703 with coded NAFLD/NASH were identified. Coded patients with NAFLD/NASH were more likely than matched controls to have diabetes, hypertension, and obesity. Baseline diagnosis of diabetes was the strongest independent predictor of a diagnosis of hepatocellular carcinoma or cirrhosis. According to real-world population data, recorded NAFLD/NASH diagnosis may increase the risk of life-threatening liver outcomes.