Elsharydah A, et al. - A retrospective observational study was designed to distinguish predictors of perioperative major complications (MC) and mortality after THA and to apply these predictors to develop a risk scoring system. This study carried a literature search using the 2006-2016 National Surgical Quality Improvement Program (NSQIP) for adult individuals who underwent primary elective THA conducted under general or neuraxial anesthesia. Researchers applied univariate and multivariate logistic regression and bootstrap analyses to select the strongest predictors for MC. This study included a total of 104,404 cases. After THA, neuraxial anesthesia is correlated with a decreased risk of MC. The results of this study indicated that the risk model developed may help with preoperative decision-making regarding the choice of anesthesia, selection of outpatient cases, and postoperative care.