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Risk prediction of in-hospital mortality in patients with venoarterial extracorporeal membrane oxygenation for cardiopulmonary support: The ECMO-ACCEPTS score

Journal of Critical Care Mar 06, 2020

Becher PM, Twerenbold R, Schrage B, et al. - Researchers studied baseline features as well as results of 8,351 venoarterial extracorporeal membrane oxygenation (VA-ECMO) procedures conducted in Germany from 2007 to 2015, to explore predictors for 30-day in-hospital mortality among patients receiving VA-ECMO for cardiopulmonary support. Total participants were 8,351 patients (71.7% male), with 3,567 having prior CPR. The mean age of the participants was 62 years. The overall 30-day in-hospital mortality was estimated to be 61%. Using randomly picked 4,175 patients, the ECMO-ACCEPTS score (a mortality prediction score) was derived that incorporated 10 independent predictors for in-hospital mortality. Strong discrimination between low and high risk of 30-day in-hospital mortality was corroborated by internal validation in the rest of the 4,176 patients. Overall, an improved risk prediction among VA-ECMO patients for refractory cardiogenic shock might be achieved with the help of the ECMO-ACCEPTS score.
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