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Risk of suicide attempt in patients with recent diagnosis of mild cognitive impairment or dementia

JAMA Jun 09, 2021

Günak MM, Barnes DE, Yaffe K, et al. - Researchers examined if patients diagnosed with mild cognitive impairment (MCI) or dementia are at increased risk of suicide attempt. In addition, they investigated potential psychiatric moderators and assessed if the relationship differs based on recency of diagnosis. In this nationwide cohort study, 5 national databases from the Department of Veterans Affairs (VA) and Centers for Medicare & Medicaid Services were integrated and all VA medical centers in the US were included. The study population comprised 147,595 older adults including 21,085 patients with MCI, 63,255 with dementia, and 63,255 in the propensity-matched comparison group. Findings revealed higher risk of suicide attempt in patients with recently diagnosed MCI and those with recently diagnosed dementia compared with those without MCI or dementia, after adjusting for demographic characteristics and medical and psychiatric comorbidities. In exploratory analyses, no psychiatric comorbidity was identified moderating the correlation between MCI or dementia and suicide attempt. Overall findings suggest the relevance of supportive services soon after diagnosis.

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