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Risk of subsequent cutaneous melanoma in moderately dysplastic nevi excisionally biopsied but with positive histologic margins

JAMA Oct 16, 2018

Kim CC, et al. - Researchers conducted this multicenter retrospective cohort study to evaluate outcomes and risk for the development of subsequent cutaneous melanoma (CM) from moderately dysplastic nevi with positive histologic margins observed for 3 years or more. For moderately dysplastic nevi with positive histologic margins, close observation with regular skin surveillance was a realistic approach to management. However, an increased risk of developing a subsequent CM at a separate site was seen in patients with two or more biopsied dysplastic nevi (with one that is a moderately dysplastic nevus).

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