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Risk of mortality between untreated and treated papillary thyroid cancer: A matched cohort analysis

Annals of Otology, Rhinology & Laryngology Feb 12, 2020

Lin JK, Sakoda LC, Darbinian J, et al. - Among 3,679 individuals with papillary thyroid cancer (PTC), researchers intended to determine if there is a link between treatment status and mortality risk. They matched 31 untreated individuals to 155 treated individuals for this analysis. In order to estimate all-cause and disease-specific mortality, HRs and 95% CIs were calculated. For untreated vs treated patients, the adjusted HRs for all-cause mortality at 5 and 10 years were 4.2 and 4.1, and for disease-specific mortality, 14.1 and 10.2. For low-risk untreated vs matched treated patients, the adjusted HRs for all-cause mortality was 0.7. Untreated PTC patients were at higher risk of death relative to treated patients, on the other hand, low-risk untreated PTC patients had a similar rate of metastasis and no increased risk of all-cause mortality.
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