Malekinejad M, Barker EK, Merai R, et al. - Men who have sex with men infected with Treponema pallidum (TP), Neisseria gonorrhoeae (NG), or Chlamydia trachomatis (CT) are at raised risk of HIV acquisition risk.

• A total of 26 studies were retrieved that yielded 39 risk ratios (RRs) (k) for HIV acquisition due to one of TP, NG, or CT.

• Risk of HIV acquisition is double or more among MSM infected with TP, NG, or CT.

• For all 3 pathogens, subanalysis RRs were ≥ 1.66; these remained statistically significant across geography and methodological characteristics.