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Risk of coronary artery disease and stroke according to sex and presence of diabetic nephropathy in type 1 diabetes

Diabetes, Obesity and Metabolism Jul 15, 2018

Harjutsalo V, et al. - Researchers sought to differentiate patients with type 1 diabetes (T1D) with different cardiovascular risk profiles via assessing the impact of different stages of diabetic nephropathy (DN) and sex on the excess and absolute morbidity of coronary artery disease (CAD) and stroke in T1D. They analyzed 4,410 patients with T1D from the Finnish Diabetic Nephropathy Study (FinnDiane) categorized by DN status and 12,434 non-diabetic control individuals. In this work, despite women displaying a several-fold increase in excess CVD risk vs men, the absolute CVD risk in men and women is the same when nephropathy is taken into account. An excess CVD risk was displayed by even normoalbuminuric patients with normal kidney function vs non-diabetic controls.

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