Wu Y, Yao JW, Xu LJ, et al. - Researchers here examined whether the risk of congenital malformations is higher in correlation with the use of β‐blockers during early pregnancy. Performing a systematic literature search was performed in PubMed, Embase and Cochrane Library, they identified 20 relevant observational studies published from database inception until February 2020. Findings suggest no correlation of exposure to β‐blockers during early pregnancy with congenital malformations or heart malformations in offspring. Further studies are required to evaluate other organ‐specific congenital malformations.