Risk of breast cancer and pre diagnostic urinary excretion of bisphenol A, triclosan, and parabens: The Multiethnic Cohort study
International Journal of Cancer May 28, 2021
Wu AH, Franke AA, Wilkens LR, et al. - Given a widespread exposure to bisphenol A (BPA), triclosan and parabens, researchers sought to investigate the impact of endocrine-disrupting chemicals (EDCs) on breast cancer risk via performing a nested case-control study within the Multiethnic Cohort (MEC). Using a sensitive and validated liquid chromatography mass spectrometry assay, prediagnostic urinary BPA, triclosan, and parabens were determined in 1,032 mostly postmenopausal women with breast cancer (48 African American, 77 Latinos, 155 Native Hawaiian, 478 Japanese American, and 274 White) and 1,030 individually matched controls. Outcomes suggest that breast cancer risk was unrelated to BPA and was weakly inversely linked with triclosan and paraben exposures in this multiethnic population,.
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