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Risk of aspirin continuation in spinal surgery: A systematic review and meta-analysis

The Spine Journal Aug 24, 2017

Goes R, et al. – This systematic review and meta–analysis evaluated all evidences on continuation of aspirin, compared peri– and post–operative blood loss and complication rates between patients who continued aspirin with those who discontinued aspirin peri–operatively in spinal surgery. Findings demonstrated no significant differences in peri–operative complications between aspirin continuation and discontinuation.

Methods

  • A meta–analysis corresponding to the PRISMA guidelines was conducted.
  • A total of 3 case series out of 1339 studies were included in the meta–analysis.

Results

  • No significant differences were observed between the aspirin–continuing group and the aspirin–discontinuing group with respect to mean operating time and mean peri–operative blood loss.
  • Both the groups reported similar and non–significant differences with regard to cardiac events, stroke, and surgical site infections.

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