Gray LEK, Ponsonby AL, Collier F, et al. - Given the antecedents and results of infants who show IgE sensitization to foods that they clinically tolerate are inquired in few investigations, and therefore, researchers tried to acquire a better knowledge of this sensitized-tolerant phenotype so that strategies for the prevention of food allergy may be informed. For this purpose, they used an Australian birth cohort (n = 1,074) and grouped the study sample into non-sensitized, sensitized-tolerant or food allergic depending on skin-prick examination and food challenge at 12 months of age. At birth, measurements were obtained for cord blood regulatory T-cell populations. Via parent report, clinical testing and repeat skin-prick examination, they evaluated subsequent childhood allergic disease. In this study, food sensitized-tolerance in infancy seemed to be related to a similar pattern of exposures, immunity and results to non-sensitized infants. By some evidence gained in this study, a high proportion of activated regulatory T cells at birth was particular to the sensitized-tolerant infants, which likely be of relevance to suppression of the clinical disease.