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Risk factors for septic adverse events and their impact on survival in advanced ovarian cancer patients treated with neoadjuvant chemotherapy and interval debulking surgery

Gynecologic Oncology Aug 23, 2018

Son JH, et al. - Researchers retrospectively reviewed the medical records of 69 patients with advanced epithelial ovarian cancer treated with neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS), to assess risk factors for septic complications during adjuvant chemotherapy and their influence on survival in these patients. An early risk factor for septic complications during adjuvant chemotherapy could be grade 3 anemia during NACT. As survival was adversely influenced, tailoring scheme and dose of adjuvant chemotherapy as well as careful follow-up evaluation were recommended for this patient group.
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