Kaufmann KB, et al. - Using data from the German Thorax Registry, researchers performed this retrospective study to determine the modifiable risk factors for post-operative pulmonary complications (PPCs) following video-assisted thoracoscopic surgery (VATS) in lung cancer patients. Of 376 patients with lung cancer, 2 underwent VATS bilobectomy, 258 had lobectomy and 116 had segmentectomy in 2016 and 2017. PPCs occurred in 114 patients (114/376; 30%). Forced expiratory volume in 1 second ≤ 60%; arterial oxygen partial pressure ≤ 60 mm Hg; duration of surgery ≥2 hours and intraoperative crystalloids ≥6 mL/kg/h were identified as 4 independent risk factors in multivariate stepwise logistic regression analysis. For avoiding an increased risk for PPCs, keeping intraoperative amount of crystalloid fluids below 6 mL/kg/h and duration of surgery below 2 hours is recommended.