Kaufmann KB, et al. - Using data from the German Thorax Registry, researchers investigated modifiable risk factors for post-operative pulmonary complications (PPCs) in lung cancer patients following video-assisted thoracoscopic surgery (VATS) in this retrospective study. They performed univariate and multivariate stepwise logistic regression analysis. Lung cancer patients who had VATS bilobectomy (n = 2), lobectomy (n = 258) or segmentectomy (n = 116) in 2016 and 2017 were included in this study. Forced expiratory volume in 1 second ≤ 60%; arterial oxygen partial pressure ≤ 60 mm Hg; duration of surgery ≥2 hours and intraoperative crystalloids ≥6 mL/kg/h are the 4 independent risk factors that were identified in the multivariate stepwise logistic regression analysis. To prevent an increased risk for PPCs, they recommend keeping intraoperative amount of crystalloid fluids below 6 mL/kg/h and a duration of surgery below 2 hours.