Yang L, et al. - Researchers examined Chinese patients who were treated with immunosuppressive therapy for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), to investigate the clinical characteristics and risk factors of severe infection in these subjects by using multivariate Cox proportional hazards models. They reported high infection rate during induction therapy in these patients. The predominant type of infection documented was bacterial pneumonia. The identified risk factors for infection included age at the time of diagnosis, smoking, baseline serum creatinine ≥5.74 mg/dl, CD4⁺ T cell< 281 μl, and intravenous cyclophosphamide therapy.