Uijl A, et al. – In a cohort of 871,687 individuals aged ≥ 55 years and free of heart failure (HF) at baseline who were identified via linking electronic health records data, researchers examined the associations between risk factors and incident HF, separately for men and women and by age category (55–64, 65–74, and > 75 years) via Cox proportional hazards analysis. Factors that were found to have a relation to HF were age, social deprivation, smoking, sedentary lifestyle, diabetes, atrial fibrillation, chronic obstructive pulmonary disease, body mass index, hemoglobin, total white blood cell count, and creatinine. Women vs men showed stronger associations of smoking, atrial fibrillation, and diabetes with incident HF. They noted that mainly modifiable risk factors and comorbidities showed robust associations with incident HF.