Risk factors for hypocalcemia and hypoparathyroidism following thyroidectomy: A retrospective Chinese population study
Cancer Management and Research Nov 23, 2017
Wang Y, et al. - Researchers performed this study to analyze the risk factors for hypocalcemia and hypoparathyroidism following thyroidectomy. The risk fctors assessed seemed to have significance for guiding surgeons to prevent the occurrence of hypocalcemia and hypoparathyroidism.
Methods
- Researchers retrospectively analyzed a total of 278 patients who underwent thyroid surgery.
- They performed univariate analysis and multivariable logistic regression to discover the risk factors for hypocalcemia and hypoparathyroidism.
Results
- In 76 (27.3%) patients, postoperative hypocalcemia occurred and in 42 (15.1%) patients, hypoparathyroidism occurred.
- The presence of postoperative hypocalcemia was significantly associated with 7 factors, namely, age (P=0.049), gender (P=0.015), lateral lymph node dissection (P=0.017), operation type (P<0.001), preoperative parathyroid hormone (PTH) level (P=0.035), operation time (P=0.001), and applying carbon nanoparticles (CNs; P=0.007).
- Postoperative hypoparathyroidism seemed to have a significant correlation with gender (P=0.014), lateral lymph node dissection (P=0.038), operation type (P < 0.001), operative time (P < 0.001), and applying CNs (P=0.001).
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