Rosen MW, et al. - Researchers examined young women with endometrial hyperplasia or cancer to evaluate their clinical traits. They conducted a retrospective chart review of 69 patients (10- to 25-year-old young women), including 13 cases with endometrial cancer or hyperplasia, 54 controls who underwent an endometrial biopsy with other benign pathologic diagnoses (controls), and 2 exclusions. As per findings, patients with endometrioid intraepithelial neoplasia or cancer display a BMI greater than 30 statistically more commonly. Although this small cohort study did not show the relation of smoking or polycystic ovary syndrome (PCOS) alone with endometrial hyperplasia or cancer, a relationship between endometrial abnormalities and multiple exposures, including smoking and BMI greater than 30 or smoking and a history of PCOS, could be present.