Peprah S, et al. - Researchers investigated risk factors for endemic Burkitt lymphoma (eBL) in children aged 0-15 years old, enrolled in this population-based case-control study, recruited from six regions in Northern Uganda, Northern Tanzania, and Western Kenya. Overall 862 suspected cases and 2,934 population-controls (response rates 98.5-100%) were included. Using standardized protocols, they processed ~40,000 vials of samples. They used risk-factor questionnaires. Using rapid diagnostic tests, they measured malaria period prevalence. They found HIV was related to elevated eBL risk. In Africa, performing networked, multisite population-based studies of eBL was feasible. Findings revealed an inverse association of eBL with socioeconomic status. They also found a positive association of eBL with inpatient malaria therapy 12 months ago and with living in areas tageted for malaria suppression. A role of malaria in eBL was supported.