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Risk factors for adverse events in emergency department procedural sedation for children

JAMA Pediatrics Aug 25, 2017

Bhatt M, et al. – An observational study was conducted to analyze the incidence and risk factors associated with sedation–related serious adverse events (SAEs). Investigations suggested that with the type of sedation medication, the incidence of adverse sedation outcomes varied significantly. Use of ketamine only was associated with the best outcomes, resulting in significantly fewer SAEs. Hence, interventions with ketamine combined with propofol or fentanyl were preferred.
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