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Risk factors for abnormal postpartum glycemic states in women diagnosed with gestational diabetes by the international association of diabetes and pregnancy study groups criteria

Journal of Diabetes Investigation Sep 17, 2020

Hung TH, Chuang YC, Chu FC, et al. - Researchers examined the rate of postpartum glycemic screening tests (PGST) in women with gestational diabetes mellitus (GDM). In addition, they sought the risk factors for abnormal PGST results. The obstetric data of 1,648 women with GDM who delivered after 28 completed weeks of gestation at Taipei Chang Gung Memorial Hospital, Taiwan, were retrospectively analyzed. At 6–12 weeks postpartum, PGST was performed with a 75‐g, 2‐h oral glucose tolerance test. Classification of the results into normal, prediabetes, and diabetes mellitus (DM) was done. PGST was undertaken by 493 (29.9%) women, in total, suggesting that less than one third of GDM women underwent PGST. Abnormal results were observed in 162 (32.9%) women, including 135 (27.4%) with prediabetes and 27 (5.5%) with DM; this suggests that around one third of the women undergoing PGST exhibit abnormal results. For postpartum DM, following were identified as the significant risk factors: insulin therapy during pregnancy, birth weight > 4000 g, and preterm birth < 37 weeks’ gestation; whereas for postpartum prediabetes, the major risk factor was prepregnancy body mass index > 24.9 kg/m2.

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