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Risk factors for 1-year graft loss after kidney transplantation: Systematic review and meta-analysis

Clinical Journal of the American Society of Nephrology Sep 27, 2019

Foroutan F, Friesen EL, Clark KE, et al. - Researchers investigated risk factors for 1-year graft loss in kidney transplant recipients, by analyzing observational studies identified from bibliographic databases from 2000 to 2017. The included studies were those that assessed the link between donor, recipient, the transplant operation, or early postoperative complications, and 1-year death-censored graft loss. They found 35 eligible primary studies, reporting 20 risk factors, amenable to meta-analysis. Findings revealed that 1-year graft survival was predicted by recipient age, donor age, standard vs extended criteria donor, living vs deceased donor, HLA mismatch, and delayed graft function. They noted that the influence of each risk factor was small.
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