Liu J, et al. - Researchers conducted a retrospective clinical study in patients with post-Kasai biliary atresia (BA) to examine the risk factors and clinical outcomes of cholangitis. Two-year follow-up data from 180 type-III BA patients were analyzed in the hospital following the Kasai procedure in 2016, including 119 individuals with cholangitis (66.11%). Study participants were further divided among the population of cholangitis into categories of early vs late cholangitis and single vs chronic cholangitis. Pathology of the liver, liver function, occurrence and frequency of cholangitis, jaundice clearance, and rates of survival were investigated. According to findings, a higher level of gamma-glutamyl transferase before Kasai is a cholangitis risk factor. Older age and higher liver fibrosis score at Kasai are recurrent cholangitis risk factors. Shorter use of prophylactic intravenous antibiotics may contribute to early cholangitis, leading to a higher incidence of cholangitis. Recurrent cholangitis is linked to earlier onset of cholangitis. Patients with cholangitis have a comparatively delayed jaundice clearance, whereas early and recurrent cholangitis may lead to lower overall survival. Findings suggested that personalized treatment considering risk factors in individual BA patients is required to prevent cholangitis, particularly early onsets, and to improve postoperative results.