Stemler J, Salmanton-García J, Seidel D, et al. - Via involving cases of invasive infection due to Rasamsonia spp. (formerly Geosmithia/Penicillium spp.) from FungiScope registry and all reported cases from the literature, researchers sought to present a knowledge base of risk factors and therapeutic decisions in invasive Rasamsonia spp. complex infection. Twenty-three invasive infections were identified due to Rasamsonia spp., six (26.1%) in the FungiScope registry. Chronic granulomatous disease, immunosuppressive treatment, haematopoietic stem cell transplantation, graft-versus-host disease, and major surgery were the main risk factors. According to findings, Rasamsonia spp. are emerging fungi causing life-threatening infections, particularly in immunocompromised and critically ill individuals. Data reported that the overall mortality rate was 39%. No preferable treatment has been identified that influences a favorable outcome. Treatment is difficult and physicians working with this patient population should be aware of a medical emergency of this infection.