Sluis WM, Linschoten M, Buijs JE, et al. - The frequency, risk factors, and outcomes of acute ischemic stroke in hospitalized patients with coronavirus disease 2019 (COVID-19) are described.

• Among a total of 2,147 patients with COVID-19, 586 (27.3%) required treatment at an intensive care unit.

• Ischemic stroke was reported in 38 patients (1.8%).

• Patients with a stroke were older.

• The risk appeared higher in patients treated at an intensive care unit (16/586; 2.7% vs nonintensive care unit, 22/1561; 1.4%).

• More common occurrence of pulmonary embolism was observed in patients with (8/38; 21.1%) vs without stroke (160/2109; 7.6%; adjusted risk ratio, 2.08 [95% CI, 1.52–2.84]).

• There appeared a higher risk of in-hospital mortality for patients with vs without stroke.

• Overall stroke patients, in majority, experienced a poor outcome.