Albergo JI, et al. - In order to gauge the role of radiotherapy, patients with non-metastatic Ewing’s sarcoma at presentation were analyzed and the prognostic factors affecting the development of local recurrence were investigated. The overall survival of patients with Ewing’s sarcoma was significantly affected by the local recurrence. Radiotherapy reduced the risk of local recurrence, for individuals with a tumor in limb, especially in those with a marginal margin of excision, however, the effect in central tumors remained less clear. The risk of local recurrence was not reduced by the radiotherapy in those who had undergone a wide margin of resection, irrespective of the histological response to chemotherapy.