Wang H, et al. – In this cohort of 60 patients, investigators examined the association of echocardiographic-derived right ventricular (RV) function and health-related quality of life (HRQOL) with systemic lupus erythematosus associated pulmonary arterial hypertension (SLE-APAH), and assessed the best echocardiographic parameter for examining RV function in these patients. They found that patients with a tricuspid annular plane systolic excursion (TAPSE) <?17?mm had a shorter 6-minute-walk-distance, lower mixed venous oxygen saturation, and higher plasma N-terminal pro-brain natriuretic peptide. Compared with patients with TAPSE ≥ 17?mm, those with TAPSE <17?mm had lower physical component summary and mental component summary scores. They also observed that echocardiographic-derived RV systolic function was significantly related to hemodynamics, with TAPSE exhibiting the strongest association of pulmonary vascular resistance with cardiac index. Findings suggested that TAPSE is a useful index for RV function assessment and is related to HRQOL in patients with SLE-APAH.