Ribavirin treatment for critically ill COVID-19 patients: An observational study
Infection and Drug Resistance Dec 14, 2021
Xu Y, Li M, Zhou L, et al. - Despite the spread of the coronavirus disease 2019 (COVID-19) pandemic all over the world resulting in high mortality, no recommendation concerning specific antiviral treatment has been made.
Researchers conducted a retrospective descriptive study involving 19 consecutive critically ill patients.
The patients were administered ribavirin at 0.15g q8h orally upon ICU admission for 7 to 21 days.
No mortality was recorded for any of the 19 critically ill COVID-19 patients (14 males and 5 females, median age 56 yr) through to the 28th day of observations; 6 patients (31.58%) were discharged from the ICU.
These patients showed good tolerability towards ribavirin.
Through increasing the virus clearance, ribavirin may benefit COVID-19 patients.
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