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Retrospective study of survival in human papillomavirus-negative oropharyngeal squamous cell carcinoma treated with primary surgery and associated prognostic factors

OncoTargets and Therapy May 05, 2018

Yuan Y, et al. - Researchers assessed the outcomes of squamous cell carcinoma of the oropharynx treated with primary surgery and determined the related prognostic factors. They performed retrospective analysis of the primary surgically treated human papillomavirus (HPV)-negative oropharyngeal squamous cell carcinoma (OPSCC) cases at their institution between 2008 and 2013. Using Kaplan–Meier analysis, they analyzed overall survival (OS), disease-specific survival (DSS), and disease-free survival (DFS). The 3-year DSS, OS, and DFS rates were 76.7%, 75.6%, and 62.8%, respectively. Surgical treatment of oropharyngeal squamous cell carcinoma provided acceptable outcomes. The identified prognostic factors included N-stage, adjuvant radiotherapy.
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