Zhong Y, et al. – Researchers undertook this study to assess the adequacy and safety of the hook wire system in the simultaneous localizations for multiple pulmonary nodules (PNs) before video–assisted thoracoscopic surgery (VATS), and to clarify the risk factors for pneumothorax associated with the localization procedure. The results confirmed that simultaneous localizations for multiple PNs applying a hook wire system before video–assisted thoracoscopic surgery procedure were safe and effective. Compared with localization for single PN, simultaneous localizations for multiple PNs were prone to the occurrence of pneumothorax. It was showed that position change during localization procedure and the nodules located in the ipsilateral lung were independent risk factors for pneumothorax.