Shields CL, Srinivasan A, Lucio-Alvarez JA, et al. - Researchers conducted the study for analyzing clinical features and long-term outcomes in patients with retinocytoma/retinoma. Over a 20-year period, the records of patients with retinocytoma/retinoma were reviewed retrospectively to compare patient age at presentation (< 4 vs ≥ 4 years), tumor type, and tumor focality (unifocal vs multifocal). The sample consisted of 2,021 patients with retinoblastoma. The rate of retinocytoma/retinoma transformation into retinoblastoma rose from 2 to 10-20 years of age in the study cohort. Increased tumor thickness was the sole factor that predicted transformation.