Brouwer N, Marinkovic M, Bleeker JC, et al. - In this study, retinal vessel oxygenation in the eyes was compared with an untreated choroidal nevus or choroidal melanoma. The noninvasive retinal oximetry (Oxymap T1) was applied to evaluate the affected and fellow eye of patients with an untreated choroidal nevus (n = 42) or choroidal melanoma (n = 45). Researchers ascertained oxygen saturation of arterioles (ArtSat) and venules (VenSat), together with the arteriovenous difference (AV-difference). Eyes with choroidal melanoma exhibited an elevated ArtSat and decreased VenSat, leading to an increased AV-difference, although retinal oximetry was not significantly altered in eyes with a choroidal nevus. Inflammation and higher metabolism may cause these variations, with larger oxygen consumption, leading to altered blood flow and intraocular oxygen relocation.