Topal OY, Celik IK, Yagmur IT, et al. - Researchers conducted the study for analyzing the outcomes of drug provocation tests (DPTs) with nonsteroidal anti-inflammatory drugs (NSAIDs) and assessing the difficulties encountered in the classification of NSAID hypersensitivity (NSAID-H) in children. Participants in the study were patients with suspected NSAID-H who were examined in the clinic between January 1, 2015, and December 31, 2018. Oral provocation tests were conducted with NSAIDs, and reactions were classified according to the European Academy of Allergy and Clinical Immunology position paper on NSAID-H. In total, 243 individuals (57.2% male patients) presented with suspected NSAID-H during the study period. In patients with no contraindications, it is necessary to conduct diagnostic tests. Due to the coexistence of indistinguishable symptoms in their history and DPTs, and the need for multiple provocation tests, characterizing these reactions in children may be challenging. Therefore, further work on this subject is required.