Savio A, et al. – Researchers aimed to distinguish resting–state networks (RSNs) in 18F–FDG PET data and compare their spatial pattern with those obtained from simultaneously acquired resting–state fMRI (functional magnetic resonance imaging) data in 22 middle–aged healthy subjects. The outcomes argue for the common neural substrate of resting–state networks and encourage testing of the clinical utility of resting–state connectivity in PET data.