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Restaging abdominopelvic computed tomography before surgery after preoperative chemoradiotherapy in patients with locally advanced rectal cancer

JAMA Oncology Dec 05, 2017

Park HJ, et al. - In patients with locally advanced rectal cancer, authors investigated restaging abdominopelvic computed tomography (CT) performed before surgery after Chemoradiotherapy (CRT) regarding its diagnostic yield and effect on postsurgical recurrence-free survival (RFS). They recognized benefits in a small fraction of patients. However, routinely performing restaging abdominopelvic CT before surgery after CRT for locally advanced rectal cancer seemed not beneficial if a thorough initial staging evaluation excluded metastasis. It seemed to have low diagnostic yield, comparable risk of harm, and no apparent gains in postsurgical RFS (possibly harmful or, at most, modest beneficial effect).
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