Hersi H, Saarinen JT, Raitanen J, et al. - Among patients 16 years or older with newly diagnosed epilepsy, researchers inquired about the interaction among the efficacy, tolerability and overall effectiveness of the first antiseizure medication. Participants were 459 patients in total. Of these, 73% of men and 60% of women were seizure‐free for at least 1 year with the first antiseizure medication. For focal epilepsy, seizure freedom rate was reported to be 67%. In patients above 60 years of age, a seizure freedom rate of 67% was estimated. Seizure freedom rates for patients with structural and unknown etiology were noted to be 61.5% and 75.3%, respectively. This work offers a more positive prediction of seizure freedom relative to earlier investigations with the onset of epilepsy at 16 years or older with findings that the first antiseizure medication conferred seizure freedom in two‐thirds of patients with new‐onset epilepsy.