Resistance towards nondepolarising muscle relaxants: Prolonged onset time: A systematic review
European Journal of Anaesthesiology Jun 14, 2019
Mørk EL, et al. - Researchers conducted this systematic review including 25 studies to evaluate the current evidence of patient groups with resistance towards nondepolarising muscle relaxants (NDMRs). They defined a prolonged onset time as a difference that exceeded 25% compared with controls. As per findings, patients with thermal injury and Duchenne's muscular dystrophy frequently have a prolonged onset time. In addition, a prolonged onset time was noted among patients with infection, oculopharyngeal muscular dystrophy, congenital heart defects, kidney failure, liver cirrhosis treated with ulinastatin along with remifentanil or intravenous fluids administered prior to NDMR.
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