Roule V, Schwob L, Lemaitre A, et al. - In order to clarify the influence of residual atherothrombotic burden (ATB) after primary percutaneous coronary intervention (PCI) on myocardial reperfusion, researchers evaluated the link between residual in-stent ATB following primary PCI measured by optical frequency domain imaging using various measurement methods and myocardial blush grade (MBG). Participants were prospectively included and comprised 60 ST-elevation myocardial infarction patients who had already received treatment with aspirin and ticagrelor. They classified patients into 2 groups based on final MBG 3 or < 3. Irrespective of the measurement method, lower ATB was detected in patients with final MBG 3 vs those with impaired MBG. Findings revealed substantial residual poststenting ATB following primary PCI in STEMI patients, even when pretreated with ticagrelor and aspirin. A seemingly significant correlation of ATB with suboptimal myocardial reperfusion, a recognized surrogate of clinical outcome, was evident.