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Research Levels of Lipoprotein (a) in patients with coronary artery disease with and without inflammatory rheumatic disease: A cross-sectional study

BMJ Open May 17, 2019

Holm S, et al. - In this cross-sectional observational, patient-based cohort study involving 67 coronary artery disease patients with inflammatory rheumatic disease (CAD/IRD) and 52 CAD patients without IRD (CAD/non-IRD), researchers desired to know whether serum lipoprotein (a) (Lp(a)) levels differed between CAD patients with and without accompanying IRD. All participants in the study were Caucasians (aged >18 years) without any clinically significant infection or malignancy. According to findings, no differences in Lp(a) levels were found between CAD/IRD and CAD/non-IRD patients and levels of Lp(a) were poorly correlated with other CAD progression risk factors including C-reactive protein. The connection between inflammation and Lp(a) levels in CVD was not supported in this analysis.
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