Moitry M, et al. – The purpose of this study is to identify whether women presenting with reactive cellular changes (RCC) on their cervical smear face an increased risk for developing high grade cervical intraepithelial neoplasia (CIN2–3) or cancer as compared with women with an entirely normal smear. This investigation demonstrated that, at seven years, women with RCC on their cervical smear face an increased risk of CIN2–3 but no significant increased risk of cancer. The distinction between entirely normal and RCC cervical smears ought to therefore not lead to particular clinical management.