Jansen H, et al. - Researchers investigated if an improved prediction of recurrent cardiovascular disease (CVD) events could be obtained with repeat measurements of high-sensitivity cardiac troponins T and I in patients with stable coronary heart disease following adjustment for various other novel biomarkers. Participants were from the KAROLA (Langzeiterfolge der Kardiologischen Anschlussheilbehandlung) study and included 873 coronary heart disease patients. Both troponins were measured nearly 9 weeks following their initial acute event (baseline) and after 12 months. For 12 years, follow-up was performed. They evaluated a combined CVD end point, and adjusted for various risk factors. After adjustment for emerging risk factors during follow-up, a consistent association of both troponins with recurrent cardiovascular events was evident, particularly seen in patients without myocardial infarction at baseline. Independent links with future CVD events were demonstrated by troponin values at 12 months of follow-up, in addition to baseline evaluations of troponins.