Mindikoglu AL, Hernaez R, Liu Y, et al. - Via obtaining data from the Department of Veterans Affairs and identifying 6,917 individuals with cirrhosis who developed acute kidney injury (AKI) during hospitalization at any of its 127 hospitals, from 2004 through 2014, researchers desired to know about long-term outcomes of AKI in patients with cirrhosis. During the index hospitalization, they used latent class analysis of serial creatinine measurements to determine the trajectories of renal function. They identified five distinct in-hospital renal trajectories: mild AKI with full improvement, severe AKI with rapid improvement, moderate AKI with partial improvement, moderate to severe AKI with partial improvement, and severe AKI with minimal improvement. They observed the pattern of renal trajectory to be linked to mortality after discharge in an analysis of almost 7,000 veterans with cirrhosis who were hospitalized for AKI. Renal trajectory patterns can be used to identify subgroups of cirrhosis patients and AKI patients who should receive intensive postdischarge management.