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Remnant cholesterol and cardiovascular mortality in patients with type 2 diabetes and incident diabetic nephropathy

Journal of Clinical Endocrinology and Metabolism Jul 26, 2021

Yu D, Wang Z, Zhang X, et al. - Researchers assessed the link between remnant cholesterol (remnant-C) and cardiovascular mortality among patients suffering from type 2 diabetes (T2D), chronic kidney disease (CKD) stages 3-5 and newly diagnosed diabetic nephropathy (DN). Study population comprised 2282 patients with above mentioned diseases enrolled between 01/01/2015 and 31/12/2016. Among participants, baseline lipid profile was analyzed and an inquiry was made for deaths with cardiovascular disease (CVD) within 2 years of baseline. A higher risk of death with CVD was found in relation to remnant-C among patients with T2D, CKD stages 3-5 and incident DN. Unlike the general population, the highest risk of cardiovascular mortality was observed in relation to the interaction of remnant-C and low-density lipoprotein cholesterol.

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