In Yang S, et al. – An analysis was carried out of the reliability and reproducibility of spectrophotometrically determined sun protection factor (SPF) from oleosome–based SPF products. It also pursued a comparison of the spectrophotometric measurements against in vivo SPF testing to establish a reliable in vitro test method as a screening assay. A reliable spectrophotometric screening method for oil body–based SPF formulas were formulated through two broadly used organic UV sunscreen actives as a case study. A high level of reproducibility and reliability was brought to light compared to the US FDA–guided in vivo SPF testing method.