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Reliability of LoSCAT score for activity and tissue damage assessment in a large cohort of patients with Juvenile Localized Scleroderma

Pediatric Rheumatology Jun 22, 2018

Agazzi A, et al. - Authors evaluated the reliability of the 2 indexes of Localized Scleroderma Cutaneous Assessment Tool (LoSCAT), the modified Localized Scleroderma Skin Severity Index (mLoSSI) and the Localized Scleroderma Skin Damage Index (LoSDI), when applied by clinicians with different experience in scoring and managing patients with JLS. They also compared LoSCAT and infrared thermography (IRT) in monitoring lesions over time. The clinical judgement in mLoSSI which showed excellent concordance was not influenced by different clinical experience in JLS, whereas in damage assessment, LoSDI was less precise and was not completely reliable in monitoring skin changes. The ability of infrared thermography to aid in the detection of disease activity was suggested in the findings. Moreover, it was found to be reliable to monitor the lesions over time.
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