Mirjan M. Nadrljanski, et al. - In this analysis, relative apparent diffusion coefficient (rADC) and ADC in B3 and B5 lesions in premenopausal female patients, added to standard morpho-dynamic breast contrast-enhanced MRI were investigated. Researchers analyzed a total of 104 individuals with histologically confirmed B3 (N1 = 52) and matched B5 lesions (N2 = 52), on MRI (1.5 T, full diagnostic protocol, diffusion-weighted imaging – b50, b850) in a retrospective analysis following the IRB approval: Atypical ductal hyperplasia (ADH, n1 = 20), Flat epithelial atypia (FEA, n2 = 11), Classic lobular neoplasia (CLN, n3 = 8), Papillary lesion (PL, n4 = 6) and Phyllodes tumor (PT, n5 = 7). For each lesion, rADC and ADC were calculated. The initial outcomes in this study, imply the highly significant difference in both ADC and rADC between B3 and B5 lesions, although morpho-dynamic features of borderline and malignant lesions may overlap.