Kirschen GW, et al. - Given the inseparable interrelationship of a patient's vital signs, and their value in providing critical information regarding hemodynamic and physiological status, researchers sought for the precise relationship between body temperature (T) and heart rate (HR) in adults. In this retrospective secondary analysis of (1) electronic medical records from a large academic center (annual ED census of 110,000) and (2) the National Hospital Ambulatory Medical Care Survey, a large CDC-sponsored weighted sample of U.S. EDs and their own large tertiary care ED, they obtained demographic and clinical data including vital signs. Inclusion of 8715 local ED visits and approximately 123.3 million estimated national adult ED visits, was done. The analysis revealed HR increase by approximately 7 bpm for every increase in T of 1 °C among adult ED patients.