Relation of timing of percutaneous coronary intervention on outcomes in patients with non-ST segment elevation myocardial infarction
The American Journal of Cardiology Sep 19, 2020
Batchelor RJ, Dinh D, Brennan A, et al. - Researchers analyzed clinical practice concerning timing targets for percutaneous coronary intervention (PCI) in non-ST segment elevation myocardial infarction (NSTEMI), within a large population cohort analysis. They used the Victorian Cardiac Outcomes Registry. They examined data from 11,852 PCIs done for NSTEMI from 2014 to 2018. Three groups of patients were defined according to time of symptom onset to PCI (< 24 hours; 24-72 hours; > 72 hours). In multivariate logistic regression, a reduced risk of 30-day mortality was observed in relation to PCI 24-72 hours and PCI > 72 hours of symptom onset, vs PCI < 24 hours. Findings revealed that among registry patients, many underwent PCI outside the 24-hour window after NSTEMI. This delay is at odds with current guideline suggestions but did not seem to be related to an elevated death risk.
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