Relation of timing of percutaneous coronary intervention on outcomes in patients with non-ST segment elevation myocardial infarction
The American Journal of Cardiology Oct 02, 2020
Batchelor RJ, Dinh D, Brennan A, et al. - Researchers used the Victorian Cardiac Outcomes Registry to analyze clinical practice concerning timing targets for percutaneous coronary intervention (PCI) in non-ST segment elevation myocardial infarction (NSTEMI), within a large population cohort study. They analyzed data on 11,852 PCIs done for NSTEMI from 2014 to 2018. Based on time of symptom onset to PCI, three groups of patients were defined (< 24 hours; 24 to 72 hours; > 72 hours). In multivariate logistic regression, a reduced risk of 30-day mortality was observed in relation to PCI 24 to 72 hours and PCI > 72 hours of symptom onset, vs PCI < 24 hours. Overall, PCI was performed in many registry patients outside the 24-hour window after NSTEMI. This delay was at odds with current guideline suggestions but did not seem to be related to an elevated death risk.
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